“Every Patent Is Designed With One Mission — To Save Lives and Elevate Global Healthcare.”

Patents & Intellectual Property Portfolio

Dr. Ravishankar Polisetty is a globally recognized innovator in the fields of cardiovascular medicine, regenerative therapeutics, integrative oncology, immunomodulation, biomedical devices, and personalized health technologies. His innovations merge clinical excellence with deep scientific inquiry into Systems Biology and Ayurveda, bringing forward high-impact solutions for deadly and chronic diseases.
With 4 patents granted, 40+ patents filed, and 16 inventions currently under search, Dr. Polisetty has developed one of the most diverse medical IP portfolios in India in the past decade.
Many of these inventions are progressing toward clinical translation, device commercialization, and international regulatory pathways.

Featured Patent Categories

1. Immunomodulatory Drug Innovations

Dr. Polisetty has developed an entire generation of plant-derived immunomodulatory compounds, supporting immune strength in cancer, autoimmune disorders, chronic infections, and metabolic decline.
Core Scientific Focus:

  • T-cell activation & cytokine modulation
  • Macrophage-driven inflammation resolution
  • Immune homeostasis for chronic disease recovery

Example Patent Families:
Punarnava, Guduchi, Piper Nigrum, Haridra, Vacha, Karavella, etc.

These formulations aim to provide steroid-free immune regulation that is both safer and scalable for global patient access.

2. Cardiovascular Regeneration & Post-Surgery Recovery

Leveraging his global cardiac surgery experience, Dr. Polisetty has invented biologically active compounds and materials to:

  • Reverse ischemic heart tissue degeneration
  • Prevent heart failure progression
  • Reduce post-operative inflammation & fibrosis

Innovations include:

  • Anti-proliferative stent-coated biopolymers
  • Natural compound-based cardiac recovery medicines

These solutions target global top-morbidity conditions — CAD, CHF & post-MI complications.

3. Oncology & Anti-Tumor Therapeutics

A powerful portfolio of novel targeted therapies designed to:

  • Stop tumor proliferation
  • Inhibit angiogenesis in cancer cells
  • Reduce side effects of chemotherapy

Technology Highlights:

  • New phthalazine derivatives active on PARP receptors
  • 24-Epibrassinolide applications for oncology
  • Polyherbal strategies for melanoma, adenomas & liver cancers

These contribute to an affordable, precision herbal-oncology revolution, especially for low-resource health systems.

4. Digital Health & Organ Action Potential Mapping Devices

A futuristic breakthrough that converts Ayurvedic pulse science into quantitative, sensor-based diagnostics.

Features:

  • Captures real-time organ action potentials
  • AI-enabled processing to detect vital abnormalities
  • Potential to act as a digital doctor assistant

Patents include:

  • Diagnostic device for organ-specific impulses
  • Action­-potential analytics for blood biochemistry detection

Core objective: turn preventive precision medicine into a daily wearable — foundation of Docture-Poly.

5. Neurological Regeneration & Brain Repair Technologies

Ground-breaking patents in neuro-repair address:

  • Hypoxic encephalopathy (oxygen-starved brain damage)
  • Multiple sclerosis recovery
  • Neuro-immune system recalibration

Therapeutic Benefits:

  • Restores neuronal pathways
  • Improves cognition & motor function
  • Limits long-term neuro-degeneration

Ideal for post-stroke, CP bypass surgery, and post-trauma patients.

6. Gut Microbiome & Metabolic-Immune Integration

These patents focus on restoring the synergy between human immunity and gastrointestinal microflora.

Outcomes Targeted:

  • Type-2 Diabetes regulation
  • Improved nutrient absorption
  • Reduced inflammatory load & autoimmune triggers

Innovations include:

  • Gut symbiosis restoration compounds
  • Regulation of secretory profiles in the Gastro-intestinal tract

This supports the future of metabolic health and preventive cardiology.

7. Allergy, Pain & Vascular Therapeutics

A diverse therapeutic cluster targeting:

  • Migraine, vascular headaches & neuropathic inflammation
  • Chronic and seasonal allergies including respiratory issues
  • Hemorrhoids and tissue-healing vascular disorders

Examples:

  • Anti-allergic formulations from Clerodundrum serratum
  • Active compounds with improved tolerance & faster relief

These products are engineered for rapid symptom control without conventional drug toxicity.

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I-PRISM Assistant