Poly Scientific Regenerative
Integrative Systems Medicine – PRISM

Bridging Ancient Wisdom with Regenerative Science.

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Future of Regeneration

I-PRISM represents a new frontier where Ayurveda meets translational biomedical research.
It is the world’s first Polyscientific framework for Regenerative and Integrative Systems Medicine, built over 32 years of bench-to-bedside work that harmonizes ancient homeostatic principles with modern cellular regeneration.

“We are not replacing medicine; we are rewriting its grammar—integrating the molecular, the doshic and the systemic into one language of healing.”

— Dr. Ravishankar Polisetty, Founder, I-PRISM & Sai Ganga Panakeia (SGP)

Origins of the Framework

• At its heart lies the Vata, Pitta and Kapha construct, an experiential description of biological resonance and equilibrium.
• When this 1 : 1 : 1 balance is achieved in 7 tissues and 42 organs regeneration naturally follows.
• This principle guided pioneering pre-clinical work on cardiac, renal, hepatic, pancreatic and neural regeneration, later translated into bedside clinical methodology for treating End-stage disease.

Impact at a Glance

Evidence-driven milestones demonstrating
sustained clinical success.

28,000 +

patients across 25 years

Decades of experience transforming patient outcomes.

95 %

reported improvement in quality of life

Meaningful progress that patients can feel every day.

63 %
achieved near drug-free survival

Long-term recovery with minimal dependence on medication.

Applications

Wide spectrum of refractory and end-stage diseases, including cardiac failure, refractory diabetes, hypertension, autoimmune disorders (SLE, MS, Scleroderma, Lupus Nephritis, RA), chronic kidney disease, liver failure, and chronic hepatitis. It also addresses IBD/IBS, psychiatric disorders, end-stage cancers, dermatological conditions such as psoriasis and vitiligo, neurological degenerations like Parkinson’s and dementia, and pulmonary diseases including asthma and COPD.

Real stories. Real healing. Real change.

  • Diagnosed with stage 4 breast cancer in 2019, I underwent chemotherapy and radiotherapy at a reputable hospital. After a brief remission, the cancer relapsed aggressively and spread throughout my body.Traditional treatments proved ineffective, leaving me with little hope. A friend recommended Dr. Ravishankar Polisetty, an Ayurvedic specialist. With his personalized regimen of herbal supplements, diet, and exercise, my condition improved dramaticallywithin months. Despite skepticism from others opted out of further chemothera and radiation, placing my trust solely in Dr. Polisetty’s care. To-thanks to his expertise and guidance, I am cancer-free-a testament to the power of
    I-PRISM.

    — Patient Testimonial .
    Mrs Kusumlata.

What Makes I-PRISM Unique

Integrating science, ethics, and innovation for a new era of integrative healthcare.

Translational Ayurveda

From ancient knowledge to Clinical Systems Medicine

Digital Integration

Powered by Docture-Poly™ diagnostic device and the VPK-42 clinical intelligence application, enabling seamless data acquisition, analysis and translational insight.

Collaborative Network

SGP | I-PRISM Academy | IIT Hyderabad | NIMA | VAP | CCIM

Evidence-Informed

Bench models validated through clinical practice

Ethical & Complementary

Aligned with mainstream medicine — never alternative

Join the Movement

Become a PRISM Doctor.

Gain certification in Polyscientific Regenerative Integrative Systems Medicine, integrate technology-enabled Ayurveda and join a global clinical-research network.

Join the first generation of PRISM doctors and pioneer integrative regeneration.

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