Institute of
Poly Scientific Regenerative
Integrative Systems Medicine – PRISM

Bridging Ancient Wisdom with
Regenerative Science.

I-PRISM is a next-generation multidisciplinary framework that prepares doctors, scientists, technologists, and business leaders for the future of healthcare by integrating advanced AI/ML, translational and regenerative medicine, and the codified wisdom of ancient medical systems. Bridging critical gaps in today’s educational models, I-PRISM creates industry-ready innovators capable of leading, transforming, and redefining global health ecosystems.

Our Academic Program Structure & Progression

Future of Regeneration

I-PRISM represents a new frontier where Ayurveda meets translational biomedical research.
It is the world’s first Polyscientific framework for Regenerative and Integrative Systems Medicine, built over 32 years of bench-to-bedside work that harmonizes ancient homeostatic principles with modern Tissue regeneration.
Turn your hospice into a place of restoration — because end-stage care should be about living well, not dying slowly.

— Dr. Ravishankar Polisetty, Founder, I-PRISM & Sai Ganga Panakeia (SGP)

Origins of the Framework

At its heart lies the Vata, Pitta and Kapha constructs – an experimental and experiential framework correlating with biochemical, metabolic, electrophysiological signatures of underlying systemic homeostasis.
When this 1 : 1 : 1 balance is achieved in 7 tissues and 42 organs regeneration naturally follows.
This principle guided pioneering pre-clinical work on cardiac, renal, hepatic, pancreatic and neural regeneration, later translated into bedside clinical methodology for treating End-stage disease.

Impact at a Glance

Evidence-driven milestones demonstrating
sustained clinical success.

28,000 +

patients across 25 years

Decades of experience transforming patient outcomes.

95 %

reported improvement in quality of life

Meaningful progress that patients can feel every day.

63 %
achieved near drug-free survival

Long-term recovery with minimal dependence on medication.

Applied Clinical Research

Wide spectrum of refractory and end-stage diseases, including cardiac failure, refractory diabetes, refractory hypertension, autoimmune disorders (SLE, MS, Scleroderma, Lupus Nephritis, RA), chronic kidney disease, liver failure, and chronic hepatitis. It also addresses IBD/IBS, psychiatric disorders, end-stage cancers, dermatological conditions such as psoriasis and vitiligo, neurological degenerations like Parkinson’s and dementia, and pulmonary diseases including Asthma and COPD.

Real stories. Real healing. Real change.

What Makes I-PRISM Unique

Integrating science, ethics, and innovation for a new era of integrative healthcare.

Translational Ayurveda

From ancient knowledge to Clinical Systems Medicine

Digital Integration

Powered by Docture-Poly™ diagnostic device and the VPK-42 clinical intelligence application, enabling seamless data acquisition, analysis and translational insight.

Collaborative Network

SGP | I-PRISM Academy | IIT Hyderabad | NIMA | BCA | BAMC

Evidence-Informed

Bench models validated through clinical practice

Ethical & Complementary

Aligned with mainstream medicine — never alternative

Join the Movement

Become a PRISM Doctor.

Gain certification in Polyscientific Regenerative Integrative Systems Medicine, integrate technology-enabled Ayurveda and join a global clinical-research network.

Join the first generation of PRISM doctors and pioneer integrative regeneration.

In Collaboration With
IIT Hyderabad
IIT Hyderabad
Johns Hopkins University
Johns Hopkins
SSSIHL
SSSIHL
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I-PRISM Assistant